Bioinformatics Research Analyst - Genomic & Molecular Pathology

Scheduled Hours40

Position SummaryThe Clinical Genomics Laboratory (CGL) is a multidisciplinary team of clinicians, scientists, engineers, analysts, and staff serving diagnostic clinical medicine in the Division of Genomic & Molecular Pathology. This team works together to ensure the safe, efficient, and reliable delivery of genomic services directly impacting patient care. We deliver on the promises of Genomic Medicine including several first to market NGS assays ranging from targeted, ultra-deep gene panels to Whole Genome Sequence (WGS) based tests for the diagnosis, monitoring, and treatment of oncological and rare disease. Additionally, the CGL is a world leader in the genetic diagnosis of disorders of somatic mosaicism, serving clinical partners in the US and internationally.

As part of the CGL Bioinformatics team, this position will sit at the intersection of cutting-edge technologies spanning Clinical Pathology, Molecular Oncology, Genetics, Genome Sequencing, Data Science, and Informatics. With input and support from senior staff and faculty, this position will be directly involved in our fast-paced, innovative team effort to validate and launch new NGS assays for our patients and clinician partners.

Job Description

Primary Duties & Responsibilities:

• Implements: Algorithms and computer software for analyzing clinical genomics data sets; Project/Data management and analysis solutions that aid in the storage, investigation and dissemination of large data sets in a clinical environment.

• Participates in developing hypotheses and experimental design including validations of new clinical NGS assays.

• Evaluates commercial and academic bioinformatics software.

• Coordinates translational research projects with other investigators and institutions.

• Assists with reporting of methods, data and results for the lab's Quality Management Plan.

Working Conditions:
Job Location/Working Conditions

• Onsite or Hybrid (2-3 days per week) schedule preferred.

• Potential for On-Call rotation.

• Normal office environment.

Physical Effort

• Typically sitting at desk or table.

• Repetitive wrist, hand or finger movement (PC Typing).

Equipment

• Office equipment.

The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.

Required Qualifications

Education:

Bachelor’s degree or combination of education and/or experience may substitute for minimum education.

Certifications:

No specific certification is required for this position.

Work Experience:

Relevant Experience (2 Years)

Skills:

Not Applicable

Driver's License:

A driver's license is not required for this position.

More About This Job

Preferred Qualifications:

• Experience with standard bioinformatics tools and databases (e.g., Illumina DRAGEN, Manta, VEP, Strelka, BWA, GATK, VarScan, Freebayes, BEDTools, ClinVar, gnomAD, OncoKB).
• Familiarity with computing clusters (e.g., IBM LSF, Slurm), cloud computing services (e.g., AWS, GCP, Azure), and containerization (e.g., Docker, Singularity).
• Proficiency with scientific programming languages (e.g., Python, R, Perl, Java), in a UNIX/Linux and/or Windows environment.
• Experience in a CAP-accredited, CLIA-licensed clinical laboratory or similar regulated environment (e.g., ISO/IEC, HIPAA, FDA).
• Knowledge of genomic reference materials, databases, and bioinformatics tools integral to NGS assay validation (e.g., NIST Genome-in-a-Bottle, GA4GH, hap.py, vcfeval, bcftools).

Preferred Qualifications

Education:

Master's degree

Certifications:

No additional certification beyond what is stated in the Required Qualifications section.

Work Experience:

No additional work experience beyond what is stated in the Required Qualifications section.

Skills:

Ability to Reason, Amazon Web Services (AWS), Analytical Decision Making, Assay Validation, Atlassian Confluence, Atlassian JIRA, Bash Command Line, Bioinformatics Tools, Biological Assay Development, Cancer Genomics, CLIA Regulations, Clinical Workflows, Cloud Applications, Cloud Storage, Communication, Computer Software Programming, Docker Container, Gene Expression Microarray, Genome Sequencing, GitHub Repositories, Git Version Control System, Group Problem Solving, Human Genomics, Linux Clusters, Next Generation Sequencing Data Analysis

GradeR09

Salary Range$43,888.00 - $75,600.00 / Annually

The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.

Questions

For frequently asked questions about the application process, please refer to our External Applicant FAQ.

Accommodation

If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.

All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.

Pre-Employment ScreeningAll external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement

Personal

• Up to 22 days of vacation, 10 recognized holidays, and sick time.

• Competitive health insurance packages with priority appointments and lower copays/coinsurance.

• Take advantage of our free Metro transit U-Pass for eligible employees.

• WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.

Wellness

• Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!

Family

• We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We’ve got you covered.

• WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.

For policies, detailed benefits, and eligibility, please visit: https://hr.wustl.edu/benefits/

EEO/AA StatementWashington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.

Diversity StatementWashington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment – fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.