Senior High Performance Computing Engineer

Career Category

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior High Performance Computing Engineer

What you will do

Let’s do this. Let’s change the world. In this vital role you will be responsible for deploying, maintaining and supporting HPC infrastructure in a multi-cloud environment. Hands-on engineering which requires deep technical expertise in HPC technology and standard methodologies.

• Implement, and manage cloud-based infrastructure that supports HPC environments that support data science (e.g. AI/ML workflows, Image Analysis).
• Collaborate with data scientists and ML engineers to deploy scalable machine learning models into production.
• Ensure the security, scalability, and reliability of HPC systems in the cloud.
• Optimize cloud resources for cost-effective and efficient use.
• Stay ahead of with the latest in cloud services and industry standard processes.
• Provide technical leadership and guidance in cloud and HPC systems management.
• Develop and maintain CI/CD pipelines for deploying resources to multi-cloud environments.
• Monitor and fix cluster operations/applications and cloud environments.
• Document system design and operational procedures.

Must-Have Skills:

• Expert with Linux/Unix system administration (RHEL, CentOS, Ubuntu, etc.).
• Proficiency with job scheduling and resource management tools (SLURM, PBS, LSF, etc.).
• Good understanding of parallel computing, MPI, OpenMP, and GPU acceleration (CUDA, ROCm).
• Knowledge of storage architectures and distributed file systems (Lustre, GPFS, Ceph).
• Experience with containerization technologies (Singularity, Docker) and cloud-based HPC solutions.
• Expert in scripting languages (Python, Bash) and containerization technologies (Docker, Kubernetes).
• Familiarity with automation tools (Ansible, Puppet, Chef) for system provisioning and maintenance.
• Understanding of networking protocols, high-speed interconnects, and security best practices.
• Demonstrable experience in cloud computing (AWS, Azure, GCP) and cloud architecture.
• Experience with infrastructure as code (IaC) tools like Terraform or CloudFormation and Git.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. Expert knowledge in large Linux environments, networking, storage, and cloud related technologies. Also, the candidate will have expertise in root-cause analysis and fix while working with a team and stakeholders. Top-level communication and documentation skills are required. Expertise in coding in Python, Bash, YAML is expected.

Good-to-Have Skills:

• Experience with Kubernetes (EKS) and service mesh architectures.
• Knowledge of AWS Lambda and event-driven architectures.
• Familiarity with AWS CDK, Ansible, or Packer for cloud automation.
• Exposure to multi-cloud environments (Azure, GCP).

Basic Qualifications:

• Bachelor’s degree in computer science, IT, or related field with 6-8 years of hands-on HPC administration or a related field

Additional Skills:

• Experience supporting research in healthcare life sciences.
• Deep, extensive experience with High Performance Computing (HPC) and cluster management
• Familiarity with machine learning frameworks (TensorFlow, PyTorch) and data pipelines.
• Certifications in cloud architecture (AWS Certified Solutions Architect, Google Cloud Professional Cloud Architect, etc.).
• Experience in an Agile development environment.
• Prior work with distributed computing and big data technologies (Hadoop, Spark).

Professional Certifications (preferred):

• Red Hat Certified Engineer (RHCE) or Linux Professional Institute Certification (LPIC)
• AWS Certified Solutions Architect – Associate or Professional

Preferred Qualifications:

Soft Skills:

• Strong analytical and problem-solving skills.
• Ability to work effectively with global, virtual teams
• Effective communication and collaboration with cross-functional teams.
• Ability to work in a fast-paced, cloud-first environment.

Shift Information: This position is required to be onsite and participate in 24/5 and weekend on call in rotation fashion and may require you to work a later shift. Candidates must be willing and able to work off hours, as required based on business requirements.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

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As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.