Research Fellow/Senior Research Fellow [LKCMedicine]

The Lee Kong Chian School of Medicine (LKCMedicine) trains doctors who put patients at the centre of their exemplary care. The School, which offers both undergraduate and graduate programmes, is named after local philanthropist Tan Sri Dato Lee Kong Chian. Established in 2010 by Nanyang Technological University, Singapore, in partnership with Imperial College London, LKCMedicine aims to be a model for innovative medical education and a centre for transformative research. The School’s primary clinical partner is the National Healthcare Group, a leader in public healthcare recognised for the quality of its medical expertise, facilities and teaching. The School is transitioning to an NTU medical school ahead of the 2028 successful conclusion of the NTU-Imperial partnership to set up a Joint Medical School. In August 2024, we welcomed our first intake of the NTU MBBS programme, that has been recently enhanced to include themes like precision medicine and Artificial Intelligence (AI) in healthcare, with an expanded scope in the medical humanities. Graduates from the five-year undergraduate medical degree programme will have a strong understanding of the scientific basis of medicine, with an emphasis on technology, data science and the humanities.

We are seeking a Research Fellow/Senior Research Fellow in Bioinformatics to join our translational respiratory research team under Associate Professor Sanjay H. Chotirmall. The role focuses on analyzing Next-Generation Sequencing (NGS) datasets (especially metagenomics) to investigate infectious and immune consequences in chronic inflammatory lung diseases such as asthma, COPD, and bronchiectasis.

Key Responsibilities:

• Develop and implement bioinformatics pipelines for NGS data analysis (predominantly metagenomics but can include RNA-seq and single-cell sequencing).

• Perform multi-omics integration to study disease mechanisms.

• Collaborate with wet lab researchers to support experimental design and data interpretation.

• Contribute to high-impact publications and mentor junior researchers.

• Ensure data management, compliance, and reproducibility of computational workflows.

Key Competencies and Requirements:

• PhD in Bioinformatics, Computational Biology, or a related field.

• Strong programming skills (R, Python) and experience with NGS data analysis.

• Proficiency in statistical and machine learning methods for biological data.

• Familiarity with high-performance computing (HPC) environments.

• Excellent teamwork, problem-solving, and communication skills.

This role offers a unique opportunity to work at the interface of computational biology and translational respiratory research, contributing to impactful discoveries in chronic lung diseases.