Principal Scientist II - Muscle Biology

Job Description Summary

Principal Scientist II – Muscle Biology
Onsite: San Diego, CA

This key role will join our collaborative and dedicated Neuroscience team. The successful candidate will utilize their scientific expertise to create and develop novel therapeutic strategies for neuromuscular disease.

Don’t miss out on this fantastic opportunity!

 

Job Description

Key Responsibilities:

• Contribute to creating and developing novel therapeutic strategies for neuromuscular disease, with an emphasis on genetically driven muscle diseases and peripheral neuropathies.
• Communicate project strategy, scientific vision, and data to key stakeholders.
• Lead and/or engage in the design, execution, and analysis of experiments to deliver high quality data and enable project decisions.
• Deliver impact to projects by following both technical and conceptual trends in the neuromuscular field.
• Develop and integrate models of neuromuscular disease using in vivo systems in collaboration with multi-disciplinary teams in BR.
• Collaborate with multidisciplinary teams, consisting of experts in molecular biology, drug discovery, biologics and chemistry.
• Expertly relay information to all levels of the organization, as well as with our external partners and collaborators.

Minimum Requirements:

• PhD in Neuroscience, neuromuscular biology, biology or a closely related field
• 4+ years of specific expertise on neuromuscular disease and/or peripheral neuropathies.
• Must possess a deep understanding of the pathophysiology of neuromuscular disease.
• Demonstrated expertise in establishing in vivo models of neuromuscular disease to study disease mechanisms.
• Exceptional proficiency in various laboratory methodologies within neuroscience and neuromuscular disease including gene expression, functional testing and imaging.
• Excellent problem-solving skills, diligent attention to detail, and the ability to work both independently and as a member of a complex matrix teams. Thinking creatively to tackle scientific and operational challenges in a fast-paced drug discovery environment
• Strong organizational, interpersonal, and communication skills. Proven track record in leading collaborative projects.
• Strict adherence to compliance with institutional policies, laboratory safety and animal welfare guidelines, and regulatory requirements.

Preferred Qualifications:

• Experience in animal models of neuromuscular disease.
• Experience in various routes of administration in rodents.

Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture

Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between $114,000 to $211,200/year for Principal Scientist II; however, while salary ranges are effective from 1/1/25 through 12/31/25, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

 

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. 

 

Accessibility and reasonable accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to us.reasonableaccommodations@novartis.com or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

 

Salary Range

$114,100.00 - $211,900.00

 

Skills Desired

Analytical Skill, Analytical Skill, Analytical Thinking, Chemical Biology, Chemistry, Clinical Trials, Collaboration, Communication Skills, Curiosity, Data, Data Analysis, Design Of Experiments, Detail-Oriented, Drug Development, Drug Discovery, Ethics, Gene Therapy, Immunology, Inventory Management, Laboratory, Lifesciences, Machine Learning (Ml), Management, Medical Research, Molecular Biology {+ 10 more}