Computational Chemistry Senior Research Scientist (Image Analytics)

Job Description

We are searching for a highly motivated computational scientist with a strong background in methods development for image analytics to join the Data & Computational Science (DCS) team at Vertex Pharmaceuticals. You will play a critical role in building the image analytics capabilities within DCS, supporting analysis of histopathology, high content, multiplexed, in vivo and materials imaging studies. An ideal candidate should have experience in applying statistical and machine learning methods towards building image analysis pipelines and strong knowledge of software development best practices. As a key contributor you will be expected to work closely with DCS colleagues and research scientists, and Vertex’s Data, Technology and Engineering (DTE) group to help in the development of scalable, production solutions. The applicant must be a demonstrated team player and is also expected to support downstream analyses, possibly integrating with other data sources such as genomics or small molecule studies. Thus, the ideal candidate will have a strong foundation in image analysis, but also a broad skillset to address data science problems.

This is a Boston, MA based hybrid/onsite position requiring 3 days/week onsite.

Key Responsibilities:

• Develop novel computational methods and pipelines for imaging data across multiple modalities to address key questions for quantifying cellular and tissue assays.
• Identify, evaluate and adopt new image analytics and AI/ML methods from various sources 
• Lead rigorous computational analyses of imaging and other biological data while developing new approaches.
• Collaborate with project teams and DCS members to identify key needs and questions that can be addressed using image analytics
• Collaborate with project teams across the company to enable best practices for image data analytics with a strong motivation for data integrity and data provenance.

Education and Experience:

• Ph.D. (or equivalent degree) in computer science, computational biology, bioengineering, physics, or a related field, or a related field and 2-5 years of productive, relevant post-doctoral employment experience, or
• MS (or equivalent degree) in similar fields and 5+ years of productive, relevant employment experience, or
• A proven track record of image analytics method development in two or more of the following areas: histopathology, high content, multi-plexed, in vivo, or materials imaging
• Strong programming skills, ideally in Python, and proficiency with workflow languages such as Nextflow, version control (git), and cloud compute environments (AWS)
• Expertise in the use of image analysis toolkits (e.g., scikit-image, OpenCV)
• Hands-on experience in customizing ML/AI methods (PyTorch, Tensorflow) for image analytics
• Excellent communication skills that can be tailored to scientists with or without computational biology expertise
• A team-oriented mindset that welcomes feedback and supports others, and a desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases.

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Pay Range:

$123,400 - $185,100

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as: 
1.    Hybrid: work remotely up to two days per week; or select
2.    On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. 
 

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com