Physical R&D Researcher II - TAPI

Who we are

TAPI is the leading international supplier of active pharmaceutical ingredients (APIs). With the industry's broadest portfolio including over 350 API products. We are the go-to global supplier for APIs, supporting 80% of top 50 global pharmaceutical companies. We are proud of our reliable history in the generic API industry dating back over 80 years, and the fact we are considered to be one of the most trusted API suppliers, these enable TAPI to lead the industry, based on our experience, expertise, technologies, and exceptional customer service.

Our employees are at the core of our success.  Our Headquartered is in Israel, TAPI employs more than 4,000 professionals at 14  sites worldwide. Our state-of-the-art production facilities are located in Italy, Hungary, the Czech Republic, Croatia, Israel, Mexico and India. Our significant ongoing investment in R&D generates a steady flow of APIs, enabling timely introduction of new products to market.

How you’ll spend your day

• Perform Polymorph screening as per guideline.
• Follow cGMP Documentation and EHS compliance at workplace
• Perform Virtual and Experimental Screen and evaluate all literature that relates to solid-state issues.
• Screen new forms by performing stress tests and File ASAP new forms in patent application
• Analyze laboratory samples by XRD, DSC, TGA and other characterization techniques.
• Assess kinetic stability and interconversions and produce scheme of all polymorphic transitions
• Produce solubility curves of different polymorphs and assess thermodynamic stability relationships
• Develop detection methods to assess polymorphic purity and monitor in the laboratory samples 
• Support the development of the crystallization process with full characterization
• Monitoring stability and physical properties of micronized/milled materials
• Perform calibration, method development, method validation, and troubleshooting using various instruments like PXRD, DSC, TGA and Particle size analyzer
• Knowledge of various regulatory guidelines w.r.t. method development, product development, and documentation.

Your experience and qualifications

Qualification: MSc Chemistry / B Tech (Chemical Engineer)

Experience: 

• 1-5 years of experience in relevant industry and profile
• Experience with quantum chemistry, molecular modeling,
• Programming in Python, R, or MATLAB.
• Experience with machine learning (ML) algorithms for chemical data (e.g., regression, clustering, neural networks).
• Familiarity with chemoinformatics libraries (e.g., RDKit, Open Babel).
• Knowledge of data visualization (Matplotlib, Seaborn, Plotly).
• Molecular docking and simulations (e.g., AutoDock, GROMACS, Gaussian).
• Use of AI/ML models for material science or drug discovery.
• Polymorph Screening experience
• Analyze laboratory samples by XRD, DSC, TGA and other characterization techniques
• Follow cGMP Documentation and EHS compliance at workplace
• Support the development of the crystallization process with full characterization

 

Internships or work experience in pharmaceutical, chemical, or biotech industries

Teva’s Equal Employment Opportunity Commitment

Teva Pharmaceuticals is committed to equal opportunity in employment. It is Teva's global policy that equal employment opportunity be provided without regard to age, race, creed, color, religion, sex, disability, pregnancy, medical condition, sexual orientation, gender identity or expression, ancestry, veteran status, national or ethnic origin or any other legally recognized status entitled to protection under applicable laws. We are committed to a diverse and inclusive workplace for all. If you are contacted for a job opportunity, please advise us of any accommodations needed to support you throughout the recruitment and selection process. All accommodation information provided will be treated as confidential and used only for the purpose of providing an accessible candidate experience.