Principal IS Architect – Clinical Computation Platform

Career Category

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Principal IS Architect – Clinical Computation Platform

What you will do

Amgen’s Clinical Computation Platform Product Team manages a core set of clinical computation solutions that support global clinical development. This team is responsible for building and maintaining systems for clinical data storage, data auditing and security management, analysis and reporting capabilities. These capabilities are pivotal in Amgen’s goal to serve patients.

The Principal IS Architect will define the architecture vision, create roadmaps and support the design and implementation of advanced computational platforms to support clinical development, ensuring that IT strategies align with business goals. The Principal IS Architect will work closely with partners across departments, including CfDA, GDO, CfOR, CfTI, CPMS and IT teams, to design and implement scalable, reliable, and hard-working solutions.

• Develop and maintain the enterprise architecture vision and strategy, ensuring alignment with business objectives
• Create and maintain architectural roadmaps that guide the evolution of IT systems and capabilities
• Establish and enforce architectural standards, policies, and governance frameworks
• Evaluate emerging technologies and assess their potential impact on the enterprise/domain/solution architecture
• Identify and mitigate architectural risks, ensuring that IT systems are scalable, secure, and resilient
• Maintain comprehensive documentation of the architecture, including principles, standards, and models
• Drive continuous improvement in the architecture by finding opportunities for innovation and efficiency
• Work with partners to gather and analyze requirements, ensuring that solutions meet both business and technical needs
• Evaluate and recommend technologies and tools that best fit the solution requirements
• Ensure seamless integration between systems and platforms, both within the organization and with external partners
• Design systems that can scale to meet growing business needs and performance demands
• Develop and maintain logical, physical, and conceptual data models to support business needs
• Establish and enforce data standards, governance policies, and best practices
• Design and manage metadata structures to enhance information retrieval and usability

What we expect of you

We are all different, yet we all use our unique contributions to serve patients.

Basic Qualifications:

• Master’s degree with 8 to 10 years of experience in Computer Science, IT or related field OR
• Bachelor’s degree with 10 to 14 years of experience Computer Science, IT or related field OR
• Diploma with 14 to 18 years of experience Computer Science, IT or related field
• Proficiency in designing scalable, secure, and cost-effective solutions.
• Expertise in cloud platforms (AWS, Azure, GCP), data lakes, and data warehouses.
• Experience in evaluating and selecting technology vendors.
• Ability to create and demonstrate proof of concept solutions to validate technical feasibility.
• Strong knowledge of Clinical Research and Development Domain
• Experience working in agile methodology, including Product Teams and Product Development models

Preferred Qualifications:

• Strong solution design and problem-solving skills
• Experience in developing differentiated and deliverable solutions
• Ability to analyze client requirements and translate them into solutions
• Experience with machine learning and artificial intelligence applications in clinical research.
• Strong programming skills in languages such as Python, R, or Java.
• Experience of DevOps, Continuous Integration, and Continuous Delivery methodology

Soft Skills:

• Excellent critical-thinking and problem-solving skills
• Good communication and collaboration skills
• Demonstrated awareness of how to function in a team setting
• Demonstrated awareness of presentation skills

Shift Information:

This position requires you to work a later shift and may be assigned a second or third shift schedule. Candidates must be willing and able to work during evening or night shifts, as required based on business requirements.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.