Scientist II, Single Cell Computational Biology

Cambridge, MA

eGenesis, Inc.

At eGenesis, we envision a world in which no one dies waiting for an organ transplant.

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COMPANY MISSIONAt eGenesis, we aspire to deliver safe and effective human transplantable cells, tissue and organs utilizing the latest advancements in genome editing. 
POSITION SUMMARYWe are seeking a highly skilled and motivated Scientist II with expertise in single cell and spatial genomics data analysis. The ideal candidate will play a key role in unraveling the cellular and spatial architecture of engineered organs and immune interactions in our translational research programs. This is a unique opportunity to drive high-impact research at the intersection of genomics, immunology, and synthetic biology.

PRIMARY RESPONSIBILITIES

  • Lead the design, analysis, and interpretation of single cell RNA-seq, ATAC-seq, and spatial transcriptomics experiments
  • Integrate multi-modal datasets (e.g., scRNA-seq, CITE-seq, spatial transcriptomics) to uncover insights into tissue remodeling and immune responses
  • Collaborate with cross-functional teams including wet lab scientists, immunologists, bioinformaticians, and translational scientists
  • Develop and implement scalable pipelines and custom analytical tools for high-dimensional single cell datasets
  • Interpret data in the context of immunological mechanisms and xenotransplantation
  • Present findings to internal stakeholders and contribute to publications and patents

BASIC QUALIFICATIONS

  • PhD with 3+ years of experience in Computational Biology, Genomics, Bioinformatics, Immunology, or a related field
  • 2+ years of postdoctoral or industry experience analyzing single cell genomics data (scRNA-seq, scATAC-seq, spatial omics)
  • Strong proficiency with R and/or Python for statistical computing and data visualization
  • Deep understanding of immune cell biology and ability to interpret immune-related transcriptional signatures
  • Familiarity with popular single cell analysis tools (e.g., Seurat, Scanpy, Cell Ranger, Loupe, Squidpy, etc.)
  • Demonstrated ability to work independently on complex data analysis problems and communicate results clearly to interdisciplinary teams
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Tags: Architecture Bioinformatics Biology Data analysis Data visualization PhD Pipelines Python R Research Statistics

Region: North America
Country: United States

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