Bioinformatics Scientist II- Remote, USA

Compensation: $115,000 - $140,000 per year. You are eligible for a Short-Term Incentive Plan with the target at 7.5% of your annual earnings; terms and conditions apply.

BI Scientist II – Remote , USA 

This position is focused on developing and improving computational pipelines for analyzing large-scale genomic data, particularly in the context of clinical diagnostics and research innovation. This role requires a mix of development experience, biological knowledge, and statistical proficiency. 

 Essential Functions

• Develop and maintain bioinformatics tools and pipelines for NGS data analysis
• Collaborate with clinical, research, and engineering teams to implement solutions for genomic interpretation
• Optimize existing pipelines for performance, accuracy, and scalability
• Support assay validation and documentation requirements for clinical accreditation
• Participate in algorithm development to identify genetic variants including SNVs, CNVs, and SVs 
• Evaluate new tools and technologies relevant to genomic analysis
• Other duties as assigned  

Qualifications

• PhD degree in Bioinformatics, Data Science, Machine Learning, Computer Science, Statistics, Biophysics, Computational Biology or a related discipline, with at least 2 years of post-doctoral or industry experience
• Alternatively, MS degree in a related field with 4+ years of industry experience
• 2+ years of experience in bioinformatics pipeline development and data analysis. Proven track record of building and deploying machine learning models in real-world applications
• Experience in analyzing large and complex structured/unstructured datasets under time constraints  
• Experience in working with clinical variant data and variant effect prediction  
• Strong background in next-generation sequencing (NGS) technologies, including analysis of genetic variants 
• Strong background in bioinformatics tools and techniques (e.g., Illumina sequencing data, NGS pipelines)   
• Proficiency with programming languages such as Python, R, or Perl
• Experience working in Unix/Linux environments
• Third-gen long-read sequencing background strongly beneficial (e.g. PacBio/ONT) 
• Familiarity with cloud-based services (AWS, GCP)  
• Excellent written and verbal communication skills with the ability to clearly present technical results to non-technical stakeholders
• Ability to work both independently and collaboratively within multidisciplinary teams

Preferred

• Familiarity with bioinformatics concepts, molecular biology, and genomics is preferred, but not required
• Familiarity with large-scale data platforms and cloud-based infrastructure (AWS, Azure, GCP) is a plus
• Experience with language models (LLMs) is a strong bonus

#LI-NK1 #LI-REMOTE

About Us:

Ambry Genetics Corporation is a CAP-accredited and CLIA-licensed molecular genetics laboratory based in Aliso Viejo, California. We are a genetics-based healthcare company that is dedicated to open scientific exchange so we can work together to understand and treat all human disease faster.

At Ambry, everyone is welcome. A career at Ambry Genetics is a chance to be part of a dynamic company that aims to improve health by understanding the relationships between genetics and human disease. We earned our reputation as industry leaders by responsibly introducing cutting-edge genetic testing solutions and continually sharing what we learn with the global scientific community.

At Ambry you will be learning, challenging yourself, and having fun while collaborating with teammates through the open exchange of ideas. Our outstanding benefits program includes 401k, medical, dental, vision, FSA, paid sick leave and generous paid time off (PTO) program. Ambry Genetics is an Equal Opportunity Employer (EOE) and we maintain a drug-free work environment.

The Company believes in second chance employment. Qualified applicants with arrest or conviction history will be considered regardless of their arrest or conviction history, consistent with local laws such as Los Angeles County Fair Chance Ordinance and the California Fair Chance Act. You do not need to disclose your criminal history or participate in a background check until a conditional job offer is made to you. After making a conditional offer and running a background check, if the Company is concerned about conviction that is directly related to the job, you will be given the chance to explain the circumstances surrounding the conviction, provide mitigating evidence, or challenge the accuracy of the background report. For the purpose of the above job description, “Essential Functions” are “Material Job Duties”.

Our salary ranges are determined by role, level, and location. The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all US locations. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training.

All qualified applicants will receive consideration for employment without regard to race (and traits historically associated with race, including, but not limited to hair texture and protective hairstyles such as braids, locks, and twists), color, creed, religion, sex, sexual orientation, gender identity, gender expression (including transgender status), national origin, ancestry, age, marital status or protected veteran status and will not be discriminated against on the basis of disability, protected medical condition as defined by applicable state or local law, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. If you have a disability or special need that requires accommodation, please contact us at careers@ambrygen.com

Ambry does not accept unsolicited resumes from individual recruiters, third party recruiting agencies, outside recruiters or firms without an executed contract in place. We are not responsible for any fees related to resumes that are unsolicited or are received by Ambry. Such resumes will be deemed the sole property of Ambry and will be processed accordingly.

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