Scientist, Computational Biology

Who we are…

Cell Signaling Technology (CST) is a different kind of life sciences company, one founded, owned, and run by active research scientists, with the highest standards of product and service quality, technological innovation, and scientific rigor for over 20 years. We consistently provide fellow scientists around the globe with best-in-class products and services to fuel their quests for discovery.

Helping researchers find new solutions is our main mission every day, but it's not our only mission. We're also dedicated to helping identify solutions to other problems facing our world. We believe that all businesses must be responsible and work in partnership with local communities, while seeking to minimize their environmental impact. That's why we joined 1% for the Planet as its first life science member, and have committed to achieving net-zero emissions by 2029.

The role...

Cell Signaling Technology (CST) is seeking a highly skilled Scientist, Computational Biologist to join the Computational Biology team within the Bioinformatics & Data Science department in the R&D organization. This role will focus on developing and applying computational approaches for immunology, BCR sequencing, proteomics, multi-omics integration, single-cell analysis, spatial biology, and epigenetics, ultimately driving scientific innovation. The successful candidate will actively collaborate with interdisciplinary teams within Bioinformatics & Data Science, including Computational Biology, Data Science, Bioinformatics Software Engineering, Informational Science, and Structural Biology. They will also work closely with other R&D departments, such as Proteomics and Molecular Biology, and cross-functional teams across the organization, including Marketing & Commercial, Data Engineering, and Lab Informatics. This position requires strong computational expertise, innovative problem-solving skills, and the ability to translate complex biological data into actionable insights. The ideal candidate will leverage diverse expertise from cross-functional teams to develop robust computational solutions, fostering scientific breakthroughs and advancing CST’s research objectives.

You'll have the opportunity to...

• Develop and implement computational pipelines for BCR sequencing, single-cell analysis, spatial biology, epigenetics, and multi-omics data integration. 
• Design scalable bioinformatics workflows for high-throughput sequencing and multi-omics datasets. 
• Apply machine learning and statistical modeling to large-scale biological data. 
• Collaborate with immunologists, biologists, and data scientists to support CST’s research.
• Integrate computational methods with R&D initiatives, including Single Cell Technologies, Proteomics, and Molecular Biology. 
• Work with Bioinformatics, Data Science, Software Engineering, and Structural Biology teams to enhance data-driven discoveries. 
• Partner with Marketing, Commercial, Data Engineering, and Lab Informatics to apply computational insights strategically. 
• Maintain documentation and reproducibility standards. 
• Communicate findings through reports and publications.

Who you are and what you bring to the team...

• Ph.D. in Computational Biology, Bioinformatics, Data Science, Immunology or a related field, with relevant postdoctoral and a minimum of 2 years of hands-on experience in the field.
• Postdoctoral experience may be considered as part of the required experience 
• Technical Expertise: Proficiency in programming languages such as Python, R, and Bash.
• Experience with bioinformatics tools for sequencing data, especially BCR sequencing and single-cell analysis. 
• Strong understanding of immunological data analysis and interpretation. 
• Hands-on experience in proteomics analysis and integrating multi-omics datasets. 
• Familiarity with machine learning applications in bioinformatics. 
• Experience working with cloud computing and high-performance computing (HPC) environments.
• Soft Skills: Strong problem-solving skills and ability to work independently. 
• Effective communication skills for interdisciplinary collaboration. 
• Ability to manage multiple projects and deadlines efficiently.

Ideally, you have...

• Proficiency in software engineering best practices, including version control (Git), workflow automation, and continuous integration/deployment (CI/CD). 
• Experience working within an Agile development environment, applying methodologies to enhance collaboration and project efficiency. 
• Demonstrated experience in structural prediction and molecular modeling, particularly in the context of antibody-antigen interactions. 
• Familiarity with containerization and orchestration technologies (e.g., Docker, Kubernetes) for scalable and reproducible computational analyses. 
• Knowledge of data visualization techniques and tools for effectively presenting complex bioinformatics data.

Physical Conditions/Physical Requirements...

• Cubicle on-site
• No wet lab work required 
• Low noise (virtual meetings, computer audio)
• Work area can be filled with collaborative discussion
• Requires the ability to sit for extended periods, use a computer keyboard and mouse, good vision and hearing for computer work/virtual meetings

What we offer...

At Cell Signaling Technology (CST), we recognize that people will always be our most important asset. Providing a safe, inclusive, and stimulating working environment that understands the importance of diversity, human dignity, and meaningful work is as important as establishing company policies that incorporate excellent health insurance and pay benefits. We recognize that the  development of people is the key to their happiness and thus ensure every employee has impactful discussions with their manager and develops actionable performance and professional development plans. Lastly, we are committed to engaging and supporting our employees in committees and philanthropy that benefit their local communities and environment through community investment programs.

Benefits

• Medical (BCBS) and Dental (Delta Dental) plans paid at 90%
• Vision Insurance
• Life Insurance, Short and Long Term Disability
• Flexible Spending accounts
• 401(k) Plan with 6% match
• Tuition Reimbursement
• Generous PTO package
• Parental Leave
• Pet Insurance
• Employee Assistance Program
• Onsite Subsidized Cafeteria
• Free Parking

Cell Signaling Technology (CST) is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, status as a veteran or as a member of the military or status in any group protected by applicable federal or state laws.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

AGENCIES

All resumes submitted by search firms/employment agencies to any employee at Cell Signaling Technology (CST) via email, the Internet, or in any form and/or method will be deemed the sole property of CST unless CST engaged such search firms/employment agencies for this position and a valid agreement with CST is in place. In the event a candidate who was submitted outside of the CST agency engagement process is hired, no fee or payment of any kind will be paid.

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