Clinical Data Analyst NGS Genomics

Ann & Robert H. Lurie Children’s Hospital of Chicago provides superior pediatric care in a setting that offers the latest benefits and innovations in medical technology, research and family-friendly design. As the largest pediatric provider in the region with a 140-year legacy of excellence, kids and their families are at the center of all we do. Ann & Robert H. Lurie Children’s Hospital of Chicago is ranked in all 10 specialties by the U.S. News & World Report.

Location

Outpatient Center in Lincoln Park - Deming

Job Description

The Clinical Data Analyst is a member of the Molecular Diagnostics laboratory team who supports the goal to provide comprehensive -omics analysis to pediatric patients treated at Lurie Children’s.  Functions include a mastery of technical knowledge of high complexity tests generating genomic data within a particular area, and analysis of this data sufficient to result in an interpretation and clinical report.  The position actively supports the Hospital’s and the Department’s Continuous Quality Improvement and customer service goals through modeling of appropriate behavior and by providing a work environment conducive to attaining these goals.

Essential Job Functions:

• Performs technical quality review of data from high complexity genetic testing methodologies such as Next-Generation Sequencing (NGS), MLPA, microarrays, fragment analysis and Sanger sequencing.

• Using existing databases and newly developed analysis tools, performs technical and clinical interpretation of genetic sequence alterations identified through Next-Generation Sequencing (NGS).

• Performs initial analysis/quality review of test data and assists the Genetic Counselors/Medical Directors in drafting preliminary patient reports for molecular genetic tests.

• In collaboration with laboratory technologists, identifies opportunities to improve data accuracy/integrity by evaluating, refining and improving analysis/variant interpretation workflows, and assists in the continued development of standard operating procedures.

• Recognizes the clinical significance of each test performed, maintains the confidential and sensitive nature of patient information and results, and adheres to HIPAA regulations for transactions, security and confidentiality, and reports results within established time frames. 

• Maintains a professional level of knowledge of molecular biology and genetics to properly analyze molecular genetic test results; in particular, in the context of abnormal or atypical findings, by conducting comprehensive literature review. Keeps current with new and evolving clinical standards and workflows, particularly for next generation sequencing and variant interpretation guidelines from ACMG.

• Participates in and successfully completes all proficiency testing. Ensures compliance with CLIA/CAP requirements and adheres to the laboratory’s documented Quality Management Plan.

• Contributes to new test method and technology development and expansion of services provided by the laboratory via direct clinical lab work and/or review of test data generated during method development and validation.

• Participates in education and mentorship of other lab staff through direct interaction and presentations. Serves as a technical resource on next-generation sequencing analysis pipelines and relates expertise to staff.

• Involved in abstract, figure, and manuscript preparation and submission, and presentations at local or national professional conferences.

• Other job functions as assigned.

Knowledge, Skills and Abilities:

• Ph.D in a field directly related to human genetics and genomics required, with a strong desire to work in a clinical environment.

• Experience analyzing Next-Generation Sequencing data (whole genome/exome, RNAseq and custom panels) with commonly used bioinformatics tools and databases preferred (e.g. Mutation Surveyor, ClinVar, OMIM, HGMD).

• Experience in Next-Generation Sequencing or molecular biology bench work highly preferred.

• Experience working in a team-based environment with strong work ethic, time management skills, and proven productivity.

• Excellent verbal and written communicator with strong technical documentation capabilities.

• Demonstrated analytical and problem-solving skills with good attention to details.

Education

PhD: Genetics (Required)

Pay Range

$83,200.00-$137,280.00 Salary

At Lurie Children’s, we are committed to competitive and fair compensation aligned with market rates and internal equity, reflecting individual contributions, experience, and expertise. The pay range for this job indicates minimum and maximum targets for the position. Ranges are regularly reviewed to stay aligned with market conditions. In addition to base salary, Lurie Children’s offer a comprehensive rewards package that may include differentials for some hourly employees, leadership incentives for select roles, health and retirement benefits, and wellbeing programs. For more details on other compensation, consult your recruiter or click the following link to learn more about our benefits.

Benefit Statement

For full time and part time employees who work 20 or more hours per week we offer a generous benefits package that includes:

Medical, dental and vision insurance

Employer paid group term life and disability

Employer contribution toward Health Savings Account

Flexible Spending Accounts

Paid Time Off (PTO), Paid Holidays and Paid Parental Leave

403(b) with a 5% employer match

Various voluntary benefits:

• Supplemental Life, AD&D and Disability

• Critical Illness, Accident and Hospital Indemnity coverage

• Tuition assistance

• Student loan servicing and support

• Adoption benefits

• Backup Childcare and Eldercare

• Employee Assistance Program, and other specialized behavioral health services and resources for employees and family members

• Discount on services at Lurie Children’s facilities

• Discount purchasing program

There’s a Place for You with Us

At Lurie Children’s we embrace and celebrate diversity and equity in a serious way. We are committed to building a team with a variety of backgrounds, skills, and viewpoints — recognizing that diverse identities strengthen our workplace and the care we can provide to the Chicago community and beyond. We treat everyone fairly, appreciate differences, and make meaningful connections that foster belonging and allyship. This is a place where you can be your best, so we can give our best to the patients and families who trust us with their care.  

Lurie Children’s and its affiliates are equal employment opportunity employers.  We value diversity and are committed to creating an inclusive environment for all employees.  All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity or expression, religion, national origin, ancestry, age, disability, marital status, pregnancy, protected veteran status, order of protection status, protected genetic information, or any other characteristic protected by law.

Support email: candidatesupport@luriechildrens.org