Research Scientist, Clinical and Translational Research

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position summary

Looking for highly-trained and passionate research scientists to lead research projects to leverage the world’s largest cancer database of comprehensive and deep molecular data and clinical outcome to advance precision medicine in oncology. The Research Scientist, Clinical and Translational Research (CTR) will manage a team of scientist and/or analysts working closely with numerous leading biopharma partners and a network (Caris Precision Oncology Alliance) of leading cancer institutions and centers. Research results will be presented at major conferences and published in top clinical oncology journals, and leveraged to inform critical elements of drug development including biomarker strategy, cohort builds and assessment, and treatment patterns in patient populations of interest. The CTR will develop and manage strategic plans for functional areas or significant projects. Help to aligns policies, products, and development efforts with strategies.

Job responsibilities:

• Carry out assigned research projects, initiated either internally or externally as collaborative efforts; apply knowledge of cancer biology, molecular genetics, and clinical oncology to ensure the quality and novelty of the projects.

• Work under the supervision of CTR leadership for study design, planning and data interpretation; work in close collaboration and synergy with data scientists on data extraction and perform the most appropriate statistical analysis.

• Communicate effectively with external stakeholders including POA collaborators, biopharma partners and/or company leadership and to formulate and refine research ideas and proposals to ensure the scientific originality and maximum impact to advancing precision oncology.

• Work closely with cross-functional teams internally or externally, including but not limited to data science team, POA Strategy team, Biopharma & business Development, Medical Affairs scientists, Bioinformatics, Molecular Science Liaison Team, Molecular Geneticists, pathologists, and statisticians.

• Draft manuscripts, conference abstracts, posters, and/or presentation slides for various audiences

• Work collaboratively with internal/external researchers on editing drafts until finalization and publication.

• Be familiar with the CMI reports, including the tests and evidence review process, in order to align research projects with the overall goal of the company.

• Stay abreast of the fast emerging scientific and clinical literature in the field of clinical oncology, share with the CTR team and medical affairs team knowledge and progress in the space.

Required Qualifications:

• Ph.D. in computational biology, statistics, bioinformatics, cancer biology, biochemistry, molecular and cellular biology or biostatistics or equivalent training and experience required.

• Extensive knowledge in cancer biology of solid tumors, deep understanding of molecular genetics and familiarity with targeted and immune therapies in cancer treatment required.

• Proficient in Microsoft Office Suite, specifically Word, Excel, Outlook, and general working knowledge of Internet for business use.

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Preferred Qualifications:

• Extensive knowledge in cancer, deep understanding of molecular genetics and familiarity with targeted and immune therapies in cancer treatment required.

• Previous research experience in the molecular diagnostic field of oncology is preferred. Strong background in biostatistics or data science is preferred.

• Understanding of clinical development and/or how translational research can impact decision making to the oncology asset journey is preferred.

• Excellent written and oral communication skills are required.

• Proven ability to work independently as well as in a team

• Strong attention to detail, well-organized; proven ability to prioritize multiple projects and to meet strict deadlines.

• Proficient with statistics and familiarity with statistical software (Python and R preferred)

Physical Demands:

• None

Training

• All job specific, safety, and compliance training are assigned based on the job functions associated with this employee.

Other

• Travel required: minimal.

Conditions of Employment:  Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification.

This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.