Vice President of Information Technology

Who we are:

Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn. 

How we work:

• PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
• COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
• BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.

How you’ll contribute:

• Develop and lead a high-performing IT organization, attracting top talent, fostering innovation, and cultivating a culture of operational excellence, agility, and continuous improvement.
• Set and execute the enterprise IT strategy to enable business growth, scientific advancement, and operational excellence, with a strong focus on scalable platforms, automation, and emerging technologies including AI and ML.
• Establish an IT portfolio governance process to prioritize and sequence initiatives, manage dependencies, mitigate risks, and drive transparency across technology investments, resourcing, and budget allocations.
• Own the IT operating model and budget, ensuring strategic investments are made in alignment with business goals and operational performance is measured and continuously improved
• Drive the development and integration of AI/ML capabilities across the organization to unlock insights, streamline operations, and enable next-generation data-driven decision-making in both R&D and corporate functions.
• Partner with executive leadership and functional heads (including R&D, Clinical, Commercial, HR, and Finance) as a trusted advisor to align technology with business priorities and accelerate digital transformation.
• Define and, if necessary, evolve the company-wide cybersecurity and risk management program, ensuring ongoing threat assessment, compliance with global regulations, and proactive incident response and recovery capabilities.
• Oversee enterprise architecture and infrastructure, ensuring secure, resilient, and scalable platforms that support hybrid work models, scientific computing, and global operations.
• Ensure enterprise-wide GxP and regulatory compliance, including implementation of validated systems for data integrity and adherence to SOX, 21 CFR Part 11, GDPR, and evolving data privacy standards.
• Champion modern data and analytics architecture, including the design and implementation of a unified data platform to support real-time reporting, advanced analytics, and AI model development.
• Optimize vendor and partner ecosystem management, including outsourced managed services, SaaS platforms, cloud providers, and data/AI partners, ensuring performance, scalability, and value alignment.
• Lead disaster recovery and business continuity planning, maintaining robust, tested protocols to ensure uptime, data integrity, and uninterrupted business operations.

Skills and experience you’ll bring:

• Proven track record of leading enterprise IT strategy in fast-paced, innovation-driven environments, preferably within biotech or life sciences.
• Deep expertise in designing and implementing systems that facilitate the organization, accessibility, and reuse of data and studies across scientific and operational teams.
• Strong background in IT portfolio management, including project prioritization, resource planning, and cross-functional program execution.
• Demonstrated success as a strategic partner to R&D, Clinical, Commercial, and G&A functions, aligning technology investments with business needs.
• Expertise in building and scaling modern, secure infrastructure, with a focus on cloud-native platforms, scientific computing, and hybrid work environments.
• Significant experience with AI/ML technologies, including identifying use cases, evaluating and implementing business-specific tools, and driving organizational adoption through training and change management.
• Robust understanding of GxP, SOX, 21 CFR Part 11, GDPR, and other regulatory requirements, with experience implementing validated systems to support compliance.
• Strong knowledge of cybersecurity and risk management best practices, including incident response planning and proactive threat mitigation.
• Track record of building and mentoring high-performing IT teams, with a focus on innovation, service excellence, and continuous improvement.
• Experience managing complex vendor ecosystems, including SaaS providers, cloud platforms, managed service partners, and AI/data technology vendors.
• Adept at budgeting, forecasting, and measuring IT performance through operational KPIs and business impact metrics.

Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment.  All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.