Postdoc (m/f/d) in Roche Diagnostic Solutions R&D Germany Program in the field of in-silico antibody development

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

Are you passionate for innovation in protein interaction analysis and generative AI for protein design? If so, this exciting opportunity at Roche Diagnostics is perfect for you. Join our R&D unit, where you will collaborate with a great team of highly skilled “in silico” and laboratory experts focused on developing cutting-edge antibodies with exceptional specificity and affinity to meet the evolving demands of in vitro diagnostics.

What We Offer:

• Impactful Work: Opportunity to work on groundbreaking projects in the dynamic field of in vitro diagnostics.

• Expert Collaboration: Work alongside world-class experts in a supportive and innovative environment.

• Professional Growth: Continuous learning and professional development opportunities.

• Innovative Environment: Be part of a forward-thinking team dedicated to making significant advancements in healthcare diagnostics.

Your Assets:

As a Physicist specializing in Protein Structure Prediction and Molecular Modeling, you will:

• Innovate: Develop new methodologies to design “in silico” antibodies for future in vitro diagnostic assays.

• Leverage AI: Utilize advanced AI tools to predict protein docking poses and molecular binding kinetics, aiming to identify the ideal antibodies.

• Algorithm Development: Create novel algorithms to enhance antibodies using both internal and publicly available datasets.

• Collaborate: Work closely with internal project teams and experts to express and test these antibodies.

• Manage Data: Maintain and expand our existing antibody databases.

Your Profile:

• You hold a PhD in (bio-)physics, (computational-) chemistry, bioinformatics, or a related field.

• You possess strong machine learning and data analysis skills, proficient in Python.

• You have experience with machine learning/deep learning frameworks like TensorFlow, PyTorch, and Keras for protein language models.

• You master multivariate analysis, dimensionality reduction methods, and modern classification techniques.

• You know protein dynamics simulation tools such as GROMACS, AMBER, or similar toolboxes (a plus).

• You are familiar with parallelization toolboxes like MPI/CUDA for high-performance computing (a plus).

• You have experience with data visualization tools such as Tableau or Spotfire (a plus).

• You thrive in collaborative team environments.

• You are curious, proactive, and driven to independently suggest and try new ideas.

• You communicate complex concepts clearly and convincingly in English, with strong presentation skills.

This position will be filled with effect September 2025 and is limited to 2 years.

Have we aroused your interest?

# If we are convinced, a telephone interview or video application will take place

# If you also manage to convince us here, the last step is an interview and presentation in the Penzberg area (Greater Munich).

Do your expectations coincide with ours? 

Then we look forward to receiving your application (CV, certificates and references). 

Before sending your application, please note that no further documents can be added subsequently.

The working location is Penzberg.

We look forward to receiving your application!

Your contact to us! With people. For people.

Do you need further support?

Please have a look at our FAQs, you will find them via https://careers.roche.com/global/en/faq.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.