Data Scientist, Computational Biology

California, US residents click here.

The job details are as follows:

Who we are

We are the first publicly-traded biotech or pharmaceutical company to take the form of a public benefit corporation. Our public benefit purpose is to provide a brighter future for patients through the development of novel pharmaceutical therapies; and technologies that expand the availability of transplantable organs.

United Therapeutics (Nasdaq: UTHR) seeks to travel down the corridors of indifference to develop treatments for rare, deadly diseases. We were founded in 1996 by a family seeking a cure for their daughter’s pulmonary arterial hypertension( PAH). Today, we have six FDA-approved therapies that treat PAH, pulmonary hypertension associated with interstitial lung disease (PH-ILD) and neuroblastoma, a rare pediatric cancer. Our near-term pipeline seeks to develop additional therapies for PAH and pulmonary fibrosis (PF).

The cure for end-stage life-threatening diseases like PAH, PH-ILD, PF, and many others is an organ transplant, but only a small percentage of donated organs are available to address the vast need. For this reason, we are working to create bio-artificial organs to address the shortage of kidneys, hearts, lungs, and livers available for transplant. We believe an unlimited supply of tolerable, transplantable organs will eliminate the transplant waiting list and cure end-stage organ diseases for which transplant is not currently an option.

Who you are:

We are looking for a single cell genomic data wiz looking to play a really valuable role in getting manufactured organs out to the patients who need them.  This person will have a lot of control over the what data sets are collectedThe Computational Lab for In Silico Molecular Biology applies computational modeling to enable in silico design and testing of lung disease therapies and manufactured organs. As part of this effort to develop an integrative multiscale lung model, the Data Scientist, Computational Biology will analyze and integrate diverse data types, including molecular, imaging, and text-based (scientific publications) to map biological processes relevant to lung disease and stem cell differentiation.

Minimum Requirements

• 5+ years of professional experience with a BA/BS in Bachelor’s Degree in computational biology, applied mathematics, or related field of study OR 3+ years of professional experience with a MA/MS in in computational biology, applied mathematics, or related field of study OR 1+ years of professional experience with a PhD in in computational biology, applied mathematics, or related field of study
• Experience in applying computational tools to single cell transcriptomic data to perform gene regulatory network inference, cell trajectory identification, and dimensionality reduction
• Expertise in statistical, machine learning methods and generative AI methods applied to high-dimensional molecular datasets, text mining, and/or imaging data
• Fluency in one or more scientific programming languages (e.g. Python, R, Julia, and/or MATLAB)
• Ability to communicate effectively with both technical and non-technical audiences as demonstrated by record of presentations and publications

Preferred Qualifications

• 1+ Experience with imaging (CT, MRI) data
• Knowledge of molecular/cellular biology, pulmonary physiology, and drug development
• Strong data visualization skills, including interactive visualization (e.g. R Shiny or d3.js)
• Proficiency with deep learning software packages

Job Location

This role is located onsite in Silver Springs, MD 4 days a week with 1 day a week working remotely.

Eligible employees may participate in the Company’s comprehensive benefits suite of programs, including medical / dental / vision / prescription coverage, employee wellness resources, savings plans (401k and ESPP), paid time off & paid parental leave benefits, disability benefits, and more. For additional information on Company benefits, please visit https://www.unither.com/careers/benefits-and-amenities

United Therapeutics  Corporation is an Equal Opportunity Employer, including veterans and individuals with disabilities.