Senior Scientist

Job Description

• Based in Singapore, the regional hub for Asia Pacific (AP) and top-ranked biopharmaceutical company on the Straits Times and Statista’s list of Best Employers in Singapore for two consecutive years (2020, 2021).

• Join the premier biopharmaceutical company that has been in Singapore for more than 25 years and in AP for over 60 years
   

Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities and robust scientific methodology we collaborate to discover the next medical breakthrough.

Summary

As a senior scientist, you will report to the Principal Scientist, Translational Sciences. We are seeking a motivated and meticulous Senior Scientist to join the Translational Sciences team at our company in Singapore. In this role, the candidate will lead the design and implementation of advanced >30 parameter flow cytometry panels for patient material profiling and developing analytical capabilities for hi-dimensional flow cytometry data. Collaborating across translational research projects, the candidate will support the generation and analysis of hi-dimensional profiling data, contribute to target discovery and prioritization for projects across a spectrum of therapeutic areas.
 

The ideal candidate will have the opportunity to stay abreast of emerging technologies, machine learning analytics and engage in external collaborations with various clinical and academic institutions to drive translational research initiatives. In addition, the ideal candidate will be capable of multitasking projects and working across teams in a collaborative environment, demonstrating strong adaptability and interpersonal skills.
 

Responsibilities:

• Design and establishment of >30 parameter flow cytometry panels for comprehensive patient material profiling in alignment with project objectives

• Build analytical capabilities for hi-dimensional flow cytometry data to extract meaningful insights and support decision-making in translational studies

• Provide expertise and support the generation of hi-dimensional profiling data from patient material across diverse translational research studies.

• Collaborate closely with colleagues from cross-functional project teams to leverage high dimensional profiling data for target discovery, target prioritization and understanding the mechanism of action of novel therapeutics

• Keep up-to-date with emerging technologies and methods, and evaluate their utility in improving existing disease model platforms in capturing key aspects of human tumor biology.

• Contribute to authoring and reviewing project proposals, scientific publications, validation reports and laboratory procedures as appropriate.

• Maintain accurate documentation of experiments and results in electronic notebooks and/or other required formats in compliance with company policies and project needs.

Required Experience and Skills:

• PhD degree in life science discipline with more than 5 years of relevant research experience

• Demonstrated track record in performing research in immunology or oncology disease area

• Experience with hi-dimensional flow cytometry and other related skillsets

• Experience with molecular biology techniques including RNA extraction, qPCR, etc.

• Experience with aseptic cell culture techniques

• Comfortable working independently as well as collaboratively in a team environment

• Strong problem solving and troubleshooting skills

• Good organization and time management skills

• Good communication and interpersonal skills

• Demonstrated success in developing and implementing novel methodologies in flow cytometry or molecular biology

• Strong publication record in peer-reviewed scientific journals.

Preferred Experience and Skills:

• Experience with spectral cytometry

• Familiarity with flow cytometry principles, experimental design, and data analysis implementing machine learning algorithms and techniques

• Experience in developing and implementing novel computational or bioinformatics approaches for analyzing high-dimensional flow cytometry data.

• Familiarity with scientific software such as FlowJo, GraphPad Prism, TIBCO Spotfire, R or Python, etc.

• Experience with lab and clinical sample inventory management

• Prior experience in mentoring and training junior researchers or postgraduate students

• If possible, please provide up to 3 individuals who can provide a reference for your work

Who we are:

 We are known as Merck & Co., Inc., Rahway, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.
 

What we look for

Imagine getting up in the morning for a job as important as helping to save and improve lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a diverse group of colleagues who pursue and bring hope to countless people who are battling some of the most challenging diseases of our time. Our team is constantly evolving, so if you are among the intellectually curious, join us—and start making your impact today.

Current Employees apply HERE

Current Contingent Workers apply HERE

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

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