Director/Senior Director, Neurodegeneration

The Opportunity

The heart of insitro’s strategy is to combine genetic and health information from large numbers of humans with biological information obtained in vitro to overcome key bottlenecks in the drug discovery process. To accomplish this, we are using cutting edge methods in machine learning linked to the systematic discovery of novel therapeutic molecules. We are putting together an incredible team of highly talented translational scientists who want to make a difference to some of society’s most pressing medical needs. In this leadership role, you will help build the neuroscience therapeutic area (TA), hire and manage staff. You will report to the Vice President, Neuroscience (Genetics) and are expected to work onsite at our office in South San Francisco, CA.

Responsibilities

• Contribute to insitro's strategy in neuroscience focusing on neurodegenerative disease
• Work cross-functionally as a project team lead to design both experimental strategies and machine learning models to help identify drug targets and biomarkers, deconvolute biology, and help stratify patients
• Lead efforts to follow up on novel neurodegeneration targets with the goal of producing viable therapeutic interventions
• Participate in & lead neuroscience external collaborations

You will be joining a growing biotech startup that has long-term stability due to significant funding, but yet is very much in formation. A lot can change in this early and exciting phase, providing many opportunities for significant impact. You will work closely with a very talented team, learn a broad range of skills, and help shape insitro’s culture, strategic direction, and outcomes. Join us, and help make a difference to patients!

 

About You

• PhD or MD/PhD in a technical field (Neuroscience, Genetics, etc.) with 8+ years of industry experience in drug discovery, incl. 4+ years as a cross-functional project team leader in an industry setting
• A scientific track record in neurodegeneration or a related area with a focus on discovery or translational biology
• Experience running cross-functional drug discovery projects
• Demonstrated track record in building partnerships or collaborations with data scientists or computational biologists, engineers and experimental biologists
• Experience leading a high-performance team, including goal setting, and contributing to a culture of effective, high-quality methods development, including their  practical implementation
• Capable of communicating effectively and collaborate with people of diverse backgrounds and job functions, including a track record of collaborating with life scientists
• Experience in translating insights from large scale human cohort data into drug discovery programs is a plus
• Passion for making a difference in the world!

 

Compensation & Benefits at insitro

Our target starting salary for successful US-based applicants for this role is $210,000 - $270,000. To determine starting pay, we consider multiple job-related factors including a candidate's skills, education and experience, market demand, business needs, and internal parity. We may also adjust this range in the future based on market data.

This role is eligible for participation in our Annual Performance Bonus Plan (based on company targets by role level and annual company performance) and our Equity Incentive Plan, subject to the terms of those plans and associated policies.

In addition, insitro also provides our employees:

• 401(k) plan with employer matching for contributions
• Excellent medical, dental, and vision coverage (insitro pays 100% of premiums for employees on our base plans), as well as mental health and well-being support
• Open, flexible vacation policy
• Paid parental leave
• Quarterly budget for books and online courses for self-development
• Support to occasionally attend professional conferences that are meaningful to your career growth and development
• New hire stipend for home office setup
• Monthly cell phone & internet stipend
• Access to free onsite baristas and cafe with daily lunch and breakfast
• Access to free onsite fitness center
• Commuter benefits

 

insitro is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

We believe diversity, equity, and inclusion need to be at the foundation of our culture. We work hard to bring together diverse teams–grounded in a wide range of expertise and life experiences–and work even harder to ensure those teams thrive in inclusive, growth-oriented environments supported by equitable company and team practices. All candidates can expect equitable treatment, respect, and fairness throughout the interview process.

#LI-Onsite

About insitro   insitro is a drug discovery and development company using machine learning (ML) and data at scale to decode biology for transformative medicines. At the core of insitro’s approach is the convergence of in-house generated multi-modal cellular data and high-content phenotypic human cohort data. We rely on these data to develop ML-driven, predictive disease models that uncover underlying biologic state and elucidate critical drivers of disease. These powerful models rely on extensive biological and computational infrastructure and allow insitro to advance novel targets and patient biomarkers, design therapeutics and inform clinical strategy. insitro is advancing a wholly owned and partnered pipeline of insights and therapeutics in neuroscience, oncology and metabolism. Since launching in 2018, insitro has raised over $700 million from top tech, biotech and crossover investors, and from collaborations with pharmaceutical partners. For more information on insitro, please visit www.insitro.com.