Senior/Staff Bioinformatics Scientist

Are you passionate about advancing the field of bioinformatics and helping researchers make groundbreaking discoveries? Join our team to lead the charge in developing innovative methods and analyses for the rapidly emerging field of epitranscriptomics. This high-impact role will place you at the intersection of cutting-edge science, technology development, and customer success.

Alida Biosciences is a VC-backed startup in San Diego pioneering innovative technologies in epigenomics to empower researchers. Our mission is to provide solutions that enable scientific breakthroughs in understanding gene regulation and epitranscriptomics, driving advancements in both fundamental research and clinical applications.

In this role, you will guide the development of customer facing software features and outputs that will provide product stickiness for the first seamless sample to answer solution for epitranscriptomic analysis. You will be part of a high functioning team of software engineers, mathematicians and bioinformatics scientists where you’ll collaborate with world class researchers on impactful science and directly support customers to maximize the potential of our state-of-the-art technologies. From custom analysis to co-authoring scientific publications, your work will push the boundaries of epigenomics research and empower customers to make breakthrough discoveries.

Key Responsibilities

• Liaise with customers to understand how they use our software outputs. Customize the outputs to fit customer needs and work with engineers to develop optimized data outputs as standard software features.
• Drive continuous software improvements including data visualization, implementation of new secondary and tertiary data analysis tools and data interactivity.
• Conduct custom bioinformatics analyses and design novel methods and algorithms for epigenomics research.
• Collaborate with internal and external researchers to analyze and interpret assay-generated datasets using innovative techniques.
• Work with commercial teams to support customers in developing new methods to unlock the full potential of our technology for scientific breakthroughs.
• Lead and support the preparation of scientific publications in collaboration with customers and partners.

Requirements

• Ph.D. in Bioinformatics, Computational Biology, or a related field (or equivalent professional experience).
• Minimum of 6 years of industry experience developing bioinformatics solutions for software products.
• Proficiency in Python programming and familiarity with Unix-based environments.
• A strong foundation in bioinformatics algorithms, machine learning, statistics and data visualization.
• Demonstrated ability to derive biological insights from large data sets using systems biology frameworks.
• Familiarity with established methods for RNA-seq and epitranscriptomic analysis, demonstrating both breadth and depth of understanding. Examples include:
• Methods like MeRIP-seq for RNA modification profiling or CHIP-Seq for histone modification detection and MACS2 for peak calling.
• DNA or RNA methylation detection using conversion chemistries (e.g. bisulfite or GLORI).
• Motif analysis and identification of enriched sequence motifs.
• Differential enrichment analysis to identify biologically significant changes.
• Excellent scientific writing skills and a track record of publication.

Benefits

As an early-stage company, we offer exceptional opportunities for our employees to engage in cross-functional roles, grow with the company, build new technologies, and launch innovative products. We offer a competitive and comprehensive employee benefits package including medical, dental, vision, 401k with company match, LTD, paid vacation, and a stock plan.

Alida Biosciences is an Equal Opportunity Employer. We do not discriminate in recruitment, hiring, training, promotion, or other employment practices for reasons of race, color, religion, gender, pregnancy, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.