Bioinformatics engineer

Orion Innovation is a premier, award-winning, global business and technology services firm.  Orion delivers game-changing business transformation and product development rooted in digital strategy, experience design, and engineering, with a unique combination of agility, scale, and maturity.  We work with a wide range of clients across many industries including financial services, professional services, telecommunications and media, consumer products, automotive, industrial automation, professional sports and entertainment, life sciences, ecommerce, and education.

The Pipelines Engineering team builds and maintains analytical bioinformatics pipelines to reliably translate raw genomic data into clinically actionable insights for a global patient population. We optimize development velocity across R&D and Engineering. We deliver high-quality, reliable, compliant production bioinformatics pipelines and associated infrastructure with global reach and scale. And we provide diagnostic tests with the “secret sauce” needed for commercial success.
The Pipelines Engineering team seeks a software/bioinformatics engineer to develop new and refine existing bioinformatics pipelines with global impact and tremendous scale. In this role, you will work as an integral part of a globally distributed development team collaborating closely with R&D to develop production algorithms from statistical models and prototypes and to create data analysis tools supporting research efforts. You will also work closely with stakeholders to define product requirements and translate requirements to corresponding software designs.

Primary responsibilities:
●   Implement new and enhance existing functionality in our portfolio of pipelines supporting client’s business
●   Lead the end-to-end delivery of functionality, from requirements to deployment 
●   Process large numerical datasets efficiently
●   Support and extend our next-generation sequencing framework
●   Troubleshoot and resolve defects, craft reliable unit tests, perform code reviews and root cause analysis
●   Continue improving processes and procedures and evangelizing best practices
●   Understand and be compliant with regulatory, security and data privacy requirements 

Qualifications:
●   BS Computer Science, Bioinformatics, Information Systems, etc. MS preferred. 
●   Data Structures / Algorithms Coursework

Knowledge, skills and abilities:
●   Containerization: Docker (preferred), Singularity
●   Orchestration: DNAnexus (preferred), SevenBridges, Azure / AWS Batch, Cromwell, Kubernetes, Toil, miniWDL, AWS Omics
●   Orchestration Language: WDL (preferred), CWL, YAML, Nextflow, Snakemake 
●   Cloud: AWS, Azure, Google, AliBaba
●   Programming Language: Java (preferred), Python, R 
●   Source control: GitLab (preferred), Bitbucket, GitHub, TFS 
●   Extensive analytic troubleshooting skills
●   Excellent communication and organizational skills, especially for problem solving under pressure
●   Strong technical documentation skills
●   Eagerness to acquire new skills in genetics
●   Ability to thrive in a fast-paced environment and manage multiple tasks independently 

Preferred Technologies:
●   High performance computing on a local cluster
●   Bioinformatics Tools: GATK, SAMtools, bedtools, bwa, primer3, etc. 
●   Security / Privacy: HIPAA, GDPR
●   Biology: Next-generation sequencing, Sanger sequencing, MLPA, PCR, Southern Blot 
●   Data science: Machine learning, deep neural networks

What we offer:

• Dynamic and supporting international teams.
• Regular assessments and performance reviews. You will have the opportunity for
• promotion, bonuses and a raise in accordance with the pace at which you develop and your
• Remote, hybrid or office work.
• 20-25 vacation days per year.
• Equipment for work, laptop and all necessary additions.
• Access to trainings and courses.
• Private health insurance.
• FIT Pass card for many sports’ facilities.

Orion is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, creed, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, citizenship status, disability status, genetic information, protected veteran status, or any other characteristic protected by law.

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