Principal Scientist, Biologics Optimization
US026 PA Spring House - 1400 McKean Rd, United States
USD 117K-201K (estimate) Senior-level Full Time
Tasks
- Apply computational and AI ML design for variant engineering
- Develop function driven optimization strategies
- Evaluate emerging technologies to accelerate optimization workflows
- Lead biologics optimization efforts
- Partner on screening cascades for mechanism of action decisions
- Plan analyze and interpret experimental results
- Present and defend scientific findings
- Translate target biology into protein engineering strategies
Perks/Benefits
- N/A
Skills/Tech-stack
Affinity maturation | Aggregation Analysis | Antibody Sequence Analysis | Antibody engineering | Biophysical characterization | Computational Biology | Data Science | Developability assessment | ELISA | Flow Cytometry | Hit selection | Library construction | Machine Learning | Mammalian display | Protein Developability | Protein Engineering | Protein Structure Modeling | Protein aggregation | Protein aggregation analysis | Protein developability assessment | Protein modeling | Protein structure | SPR | Sequence analysis | Sequence liabilities analysis | Sequence prioritization | Specificity engineering | Stability analysis | Structure modeling | Thermal stability | Thermal stability analysis | Yeast Display
Education
Roles
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