Scientist II/Senior Scientist, Computational Chemistry, Drug Discovery
Cambridge, MA USA; London, UK; San Francisco, CA USA
USD 140K-217K Senior-level Full Time
Tasks
- Advise compound prioritization tradeoffs across programs
- Apply protein ligand binding modeling for hypothesis generation design and prioritization
- Build adapt or guide open source workflows for docking virtual screening SAR and property modeling
- Define computational chemistry tools and workflow inputs outputs and interpretation
- Establish validation standards review protocols and guardrails
- Evaluate agent generated drug discovery plans for chemical coherence
- Evaluate molecular design ideas and identify weak unsupported chemistry
- Lead computational chemistry strategy for live drug discovery programs
- Monitor and review computational chemistry workflows for scientific validity
- Partner with medicinal chemists and biologists to improve AI discovery loops
- Translate computational chemistry judgment into tool workflow benchmark and decision requirements
Perks/Benefits
- Commuter benefits
- Company Subsidized Lunch Program
- Educational assistance
- Employer paid life and disability insurance
- Flexible time off
- Medical/Dental/Vision insurance
- Paid parental leave
Skills/Tech-stack
ADMET | Biopython | Cheminformatics | Computational Chemistry | Conformer generation | Docking | FEP | Ligand binding | MDAnalysis | MMGBSA | Molecular Design | Molecular Dynamics | Molecular property prediction | Molecular simulation | Open Source | Open Source Software | OpenMM | Pharmacophore modeling | Property Prediction | Protein Ligand | Protein-ligand binding | Python | QSAR | RDKit | SAR modeling | Virtual Screening
Education
Regions
Countries
States
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