Senior/Principal Scientist, Analytical Cell Line Engineering and Bioassay Development
USA - MA - Lexington, United States
USD 154K-242K Senior-level Full Time
Tasks
- Assess genomic and copy number characteristics
- Author and review technical reports and protocols
- Characterize stable mammalian cell lines
- Conduct clone screening and clonal isolation
- Contribute to regulatory documentation
- Design plasmid and vector constructs
- Develop and implement bioassay methods
- Develop reporter gene assays
- Develop signaling pathway assays
- Establish technical standards and best practices
- Evaluate potency assay performance
- Execute experimental plans and interpret data
- Identify technical risks and recommend solutions
- Lead analytical cell line design and generation
- Mentor junior scientists and review experimental design
- Perform transfection transduction and stable integration
- Support technology transfer to internal and external partners
Perks/Benefits
- N/A
Skills/Tech-stack
Analytical Cell Banking | Assay Development | Cell Banking | Cell imaging | Cell line development | Clonal Isolation | Clone screening | Copy number analysis | Cytometry data analysis | Cytotoxicity assays | DNA Sequencing | Data Analysis | Data Integrity | DdPCR | Documentation Practices | Expression Stability | Flow Cytometry | Flow Cytometry Data Analysis | Flow cytometry data | Fluorescence Detection | Genomic Characterization | Good documentation | Good documentation practices | High Throughput | High Throughput Screening | Luminescence Detection | Number analysis | Potency Assay Development | Potency assay | Proliferation assays | QPCR | Regulatory Compliance | Reporter assays | Signaling Pathway Assays | Stable cell line | Stable cell line development | Technology Transfer | Transduction | Transfection | Vector design
Education
Roles
Principal | Principal Scientist | Scientist | Senior Scientist
Regions
Countries
States
Cities
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