Scientist I, Quantitative Systems Pharmacologist
Redwood City, California, United States
USD 119K-149K Mid-level Full Time
Tasks
- Abstract physiological biological elements into models
- Build internal infrastructure for data transfer quality control
- Calibrate and validate dynamical system models
- Design combination dosing regimens
- Design in silico experiments to test model assumptions
- Develop validate execute refine PBPK models
- Develop validate execute refine QSP models
- Develop validate execute refine semi mechanistic PK PD models
- Develop validate execute tumor growth models
- Document models assumptions analyses and visualizations
- Perform in silico simulations for mechanistic questions
- Project clinical exposure and efficacious doses
- Provide model support for clinical translation
- Survey literature to define mechanistic assumptions
- Visualize and communicate modeling results
Perks/Benefits
- N/A
Skills/Tech-stack
Differential Equations | Julia | MATLAB | Mathematical Modeling | Mixed-effects | Monolix | Nonlinear Mixed Effects | Nonlinear systems | Nonmem | Optimization | Ordinary differential equations | Parameter inference | Pharmacodynamic modeling | Pharmacokinetic modeling | Physiologically Based Pharmacokinetics | Python | Quantitative systems | Quantitative systems pharmacology | R | SimCYP | Simbiology | Statistics | Systems pharmacology
Education
Regions
Countries
States
Cities
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