Senior Scientist (all genders) - Computational Design for Biologics
Wuppertal-Aprath, North Rhine Westfalia, DE
EUR 77K-93K Senior-level Full Time
Tasks
- Assess aggregation risk
- Assess solubility risk
- Build modeling pipelines for affinity
- Build modeling pipelines for developability assessment
- Build modeling pipelines for manufacturability assessment
- Build modeling pipelines for specificity
- Build modeling pipelines for stability
- Characterize protein protein interactions
- Characterize protein-ligand interactions
- Communicate results through reports visualizations and presentations
- Connect targets with therapeutic modalities
- Define lead finding strategies
- Design and optimize antibodies using AI driven methods
- Design and optimize antibodies using computational methods
- Design biomolecules
- Design novel antibodies and biologics therapeutics
- Develop automated workflows for candidate generation scoring selection and data integration
- Evaluate PTM liability
- Generate and prioritize design hypotheses
- Identify druggable pockets and epitopes
- Initiate drive drug discovery projects
- Integrate biophysical assay and literature data
- Integrate structural sequence and omics data
Perks/Benefits
- Childcare support
- Coaching and mentoring
- Flexible work arrangements
- Free health checks
- Hybrid work model
- Inclusive work environment
- Learning and development
- Summer camps
- Time Off for Elder Care
Skills/Tech-stack
Aggregation Prediction | Antibody Design | Artificial Intelligence | Binding assays | Bioinformatics | Biophysical characterization | Biophysics | Cloud Computing | Computational Biology | Computational Chemistry | Container Technologies | Data integration | De Novo | De Novo Binder Generation | Developability Screening | Epitope mapping | Free Energy Scoring | Free energy | Functional assays | HPC | Ligand docking | Machine Learning | Molecular Dynamics | PTM analysis | Peptide Modeling | Physics Based Scoring | Protein Ligand | Protein Structure Prediction | Protein modeling | Protein structure | Protein-ligand docking | Solubility Prediction | Structural Biology | Structure prediction | Workflow Orchestration
Education
Roles
Regions
Countries
States
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