Principal Scientist, Biologics Optimization
US026 PA Spring House - 1400 McKean Rd, United States
USD 117K-201K (estimate) Senior-level Full Time
Tasks
- Build libraries and prioritize sequences
- Define functional hypotheses and screening cascades
- Design variants using computational and AI ML approaches
- Develop function driven optimization strategies
- Draft patent applications manuscripts protocols SOPs technical reports
- Evaluate emerging technologies to accelerate optimization workflows
- Integrate antibody sequence structure developability and function
- Lead biologics optimization efforts
- Lead project teams and manage optimization timelines
- Plan analyze and interpret experimental results
- Present and defend scientific findings
- Translate target biology into protein engineering strategies
Perks/Benefits
- N/A
Skills/Tech-stack
Aggregation assay | Antibody engineering | Artificial Intelligence | Computational Biology | Data Science | ELISA | Flow Cytometry | Library construction | Machine Learning | Mammalian display | Molecular Modeling | Protein Engineering | Protein Sequence | Protein Structure Modeling | Protein sequence analysis | Protein structure | Protein visualization | SPR | Sequence analysis | Sequence prioritization | Stability analysis | Structure modeling | Thermal stability | Thermal stability analysis | Yeast Display
Education
Roles
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