Scientist II/Senior Scientist, Computational Biophysics
Cambridge, MA USA; London, UK; San Francisco, CA USA
USD 140K-217K Senior-level Full Time
Tasks
- Advise teams on workflow suitability and limitations
- Build validated RBFE and ABFE workflows
- Build validation benchmarks and acceptance criteria
- Convert biophysics protocols into tools APIs and guardrails
- Define requirements for agent usable computational biophysics tools
- Design and validate molecular simulation workflows
- Establish standards for system setup and quality control
- Evaluate and integrate open source simulation and free energy tools
- Identify and mitigate simulation failure modes
- Implement automated checks for chemical series and ligand pose
- Scale workflows across GPU fleets with reproducibility and traceability
Perks/Benefits
- Commuter benefits
- Disability insurance
- Educational assistance
- Life insurance
- Medical/Dental/Vision
- Paid parental leave
- Paid time off
- Subsidized lunch
Skills/Tech-stack
ABFE | Absolute Binding Free Energy | Binding free energy | Distributed Scientific Computing | Equilibration | Force Field | Free energy | Free energy perturbation | GPU Computing | Ligand binding | MMGBSA | Molecular Dynamics | Molecular Parameterization | Molecular simulation | OpenFE | OpenMM | Protein Ligand | Protein-ligand binding | RBFE | Regression testing | Relative Binding Free Energy | Sampling | Scientific Computing | Scientific workflow | Scientific workflow automation | Validation Benchmarks | Workflow automation
Education
Regions
Countries
States
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