Principal Scientist, Computational Protein Design
325 Binney St - Cambridge - USA - MA, United States
USD 142K-256K Senior-level Full Time
Tasks
- Build computational to experimental design platform
- Collaborate with cross-functional teams to validate models
- Establish off target screening strategies
- Evaluate and deploy computational protein design methods
- Extend protein design to enzymes and functional domains
- Identify technologies datasets and partnerships to accelerate workflows
- Lead computational protein design campaigns
- Monitor literature and apply machine learning methods
- Optimize TCR and antibody binders
Perks/Benefits
- Discretionary year end shutdown
- Family planning benefits
- Fitness support
- Healthcare benefits
- Mental health support
- Mindfulness support
- Paid time off
- Sabbatical
- Savings and investments
- Volunteer days
- Wellness programs
Skills/Tech-stack
Active Learning | AlphaFold-Multimer | Alphafold | Binder Design | Binding assays | Cell Based Functional Assays | Computational protein design | Data Engineering | De Novo | De novo binder design | Deep Mutational Scanning | Developability Assays | Diffusion Models | Flow Based Generation | Functional assays | Generative Design | Interface Scoring | Inverse Folding | Language Models | Machine Learning | Mammalian display | Molecular Docking | Molecular Dynamics | Molecular recognition | Multi-Objective Optimization | Multimer Binding Assays | Mutational Scanning | Objective optimization | Phage display | Protein Design | Protein Engineering | Protein Language Models | Protein structure | ProteinMPNN | PyRosetta | Python | RFdiffusion | Rosetta | Structure Informed Design | Tetramer Binding Assays | Yeast Display
Education
Roles
Regions
Countries
States
Cities
Related jobs
-
AI Research Scientist USD 84K-128K3D Scene | 3D Scene Generation | Artificial Intelligence | Autonomous Driving | Embodied intelligenceEntry-level Full Time Internship圣何塞12h ago
-
Faculty Position in Data Science – Radiation Oncology USD 128K-180KArtificial Intelligence | Big Data | Clinical data | Data Engineering | Data integrationContinuing education | Dental insurance | FSA | HSA | Medical insuranceSenior-level Full TimeRochester, MN, United States17h ago
-
A/B | A/B Testing | Apache Hive | Apache Spark | B testingEntry-level InternshipSeattle, Washington, United States17h ago
-
(General Hire) Machine Learning Scientist Graduate (TikTok Recommendation) - 2027 Start (PhD) USD 119K-177KAlgorithms | C plus plus | C# | Data Structures | Deep learningEntry-level Full TimeSan Jose, California, United States17h ago
-
Computer Vision | Distributed Training | Language Models | Language Processing | Large Language ModelsCareer growthEntry-level Full TimeSan Jose, California, United States17h ago
-
Machine Learning Engineer Graduate (TikTok-Data-Search-Visual Search) - 2027 Start (PhD) USD 136K-205KComputer Vision | Data Mining | Distributed Systems | Evaluation | Information RetrievalEntry-level Full TimeSan Jose, California, United States17h ago
-
3D Modeling | 3D representations | Autoregressive models | Data strategy | Deep learningSenior-level Full TimeSan Jose, California, United States17h ago
-
Research scientist - AI Infra - Global Frontier Tech Recruitment Program - 2027 Start (PhD) USD 212K-387KAI Memory Systems | AI memory | Artificial Intelligence | Benchmarking | CPU SchedulingNone Full TimeSan Jose, California, United States17h ago
-
3D Gaussian Splatting | 3D Scene | 3D Scene Reconstruction | Architecture Optimization | Context MemorySenior-level Full TimeSan Jose, California, United States17h ago
-
Data Scientist, Global E-commerce USD 100K-198KA/B | A/B Testing | B testing | Data Mining | Data VisualizationMid-level Full TimeSeattle, Washington, United States17h ago
-
Research Data Scientist, Ads Metrics, Ads Experiences USD 147K-210KData Analysis | Data Modeling | Machine Learning | Python | RMid-level Full TimeMountain View, CA, USA18h ago
-
Research Data Scientist, Ads Metrics, Core Metrics USD 147K-210KData Modeling | Experiment design | Machine Learning | Python | RMid-level Full TimeNew York, NY, USA18h ago
-
AWS | Agile | Data Science | Databricks | LLMTravel expenses coveredEntry-level Full Time InternshipChicago, IL, United States1d ago
-
AWS | Artificial Intelligence | Databricks | Generative AI | Language ModelsHands-on experience | Mentorship | TrainingNone Full TimeNew York, NY, United States1d ago
-
Decision Scientist Senior USD 148K-247KAutomation | Causal Inference | Data Pipelines | Experimentation | Key Performance IndicatorsSenior-level Full TimeCalifornia - San Francisco, United States1d ago
-
Investigative Data Scientist/AI Engineer USD 96K-163KAgentic Workflows | Cloud Computing | Data Engineering | Data Visualization | Equities401k match | Education assistance | Employee stock purchase program | Gym membership discounts | Health spending accountMid-level Full TimeWashington DC, United States1d ago
-
Causal Inference | Data Manipulation | Difference-in-differences | Electronic medical records | Geospatial analysisMid-level Full Time525 E Mound Street, United States1d ago
-
Fraud Data Scientist II USD 100K-134KApache Spark | Component analysis | Data Cleansing | Data Governance | Data Preparation401k plan | Dental insurance | Disability insurance | Health insurance | Life insuranceSenior-level Full TimeCharlotte NC - 2320 Cascade Pointe …1d ago
-
Senior-level Full TimeCAPA401, United States1d ago
-
Data Scientist II USD 104K-134KApache Spark | Calculus | Component analysis | Data Cleansing | Data Governance401k matching | Dental insurance | Disability insurance | Health insurance | Life insuranceSenior-level Full TimeAtlanta GA - 303 Peachtree Street …1d ago
-
AI Inference | AI orchestration | Agent systems | Agentic AI | DeepSeekDental insurance | Employee assistance program | Flexible paid vacation and sick leave | Flexible spending account | Health insuranceSenior-level Full TimeFTC03 - Ft. Collins, CO B-3 …1d ago
-
Senior Applied Measurement & Data Scientist USD 119K-258KCausal Inference | Containerization | Dash | Data Engineering | Data PipelinesBackground Investigation required | DoD security clearance required | Travel opportunitiesSenior-level Full TimePittsburgh, United States1d ago
-
Artificial Intelligence | CI/CD | Cloud Computing | Code review | Deep learningSenior-level Full TimeLocation Irvine, California1d ago
-
Senior Data Scientist USD 97K-145KCloud Computing | Containers | Data Modeling | Data Quality | Data VisualizationEmployee engagement programs | Health insurance | Inclusion and Belonging Culture | On-site work requirementSenior-level Full TimeNYP/Weill Cornell Medical Center, United States1d ago
-
Data Scientist USD 74K-111KAmazon Web Services | Azure | Bias detection | Claims data | Cloud ComputingComprehensive benefits | Health and family support | Inclusion and respect cultureSenior-level Full TimeNYP/Weill Cornell Medical Center, United States1d ago