Senior Director - Computational Drug Discovery

Tasks

• Build FAIR data foundations
• Evaluate pharmacology and ADME developability
• Execute Research AI strategy
• Implement MLOps and reproducible computing
• Integrate LLMs and agentic orchestration
• Integrate computational input into DMPK risk and CMC properties
• Lead computational chemistry programs and portfolio
• Manage academic biotech and tech collaborations
• Mentor and grow computational drug discovery team
• Perform target evaluation and modality selection
• Prioritize molecules for synthesis and testing
• Represent company at conferences and consortia
• Set computational strategy and vision
• Support structure based design and machine learning decisions
• Train and deploy domain specific foundation models

Perks/Benefits

• N/A

Skills/Tech-stack

ADMET | Activity modeling | Agentic Orchestration | Aggregation Propensity Analysis | Complex modeling | CryoEM | DMPK | Developability | Diffusion Models | Docking | Embeddings | FAIR-Data | FEP | Generative Modeling | Homology Modeling | Immunogenicity Risk | Language Models | Large Language Models | MLOps | Machine Learning | Molecular Dynamics | Propensity Analysis | Protein Engineering | QM/MM | Reproducible computing | Sequence Activity Modeling | Solubility Prediction | Stability Prediction | Structure prediction | TI | Xray Crystallography